Rapamycin is a drug commonly used to prevent rejection of organ transplant by the body. The drug is also known as Sirolimus, and it is used to coat coronary stents and rare lung disease treatment. Rapamycin is marketed as Rapamune and is mostly referred to as the cancer drug. Sirolimus was first isolated in 1972 and people used it as an antifungal agent. With time, researchers discovered that the drug had remarkable immunosuppressive properties and physicians abandoned using it as an anti-fungal agent.
Mikhail Blagosklonny and the Use of Rapamycin to Increase Life Span
Mikhail Blagosklonny is a renowned scientist specializing in the study of aging and cancer. He focuses his research mostly on cancer and cancer therapies. He has immensely contributed to the field of science. According to his studies, Rapamycin can be used to increase lifespan in human beings and advocates for its use. Here are some reasons that make Rapamycin the best medicine: The drug has immunosuppressant properties and is used to prevent organ rejection by the body. Usually, the human body reacts to a new organ by rejecting it leading to failure of the transplantation process. For this reason, organ transplant patients are given anti-rejection drugs commonly known as immunosuppressive drugs or calcineurin inhibitors. Prolonged use of anti-rejection medications has adverse effects on body organs especially the kidneys. However, Rapamycin has been shown to have low levels of toxicity towards the kidneys making it the best immunosuppressive drug.Rapamycin is ideal for treating a rare disease called hemolytic-uremic syndrome. The condition is a combination of low platelet count, anemia, and kidney failure leading to renal failure. Patients are forced to permanently undergo dialysis with the only corrective measure being undergoing kidney transplantation. After a kidney transplant, patients have to take immunosuppressive drugs, and this increases the chances of the new kidney contracting the same disease. Because of Rapamycin’s low toxicity levels towards kidneys, it significantly reduces the chances of the transplanted kidney contracting the same condition.
Mikhail Blagosklonny’s Oncology Plans
The dream of Mikhail Blagosklonny is to provide the best treatment to people around the globe regardless of their economic standing. In his medical research where he studies cancer and aging, the professor is interested in the connection between the two and why cancer is widespread in older people. His research has been instrumental in the field of oncology. Not only is Mikhail a prominent researcher, but he is an oncology expert who continues to inspires his peers and students. He has many students under him who will take up the mantle from him and expand his research.In his cancer research, the researcher is more interested in Rapamycin because the drug displays some unique characteristics. For instance, the drug has anti proliferation properties, which have been shown to help treat cancer. If taken in right doses, the drug has the ability to enhance the body’s immune system towards the tumors. Alternatively, Rapamycin has been shown to promote tumor regression, and this helps it minimize cancer risk in people with organ transplants.